Recombinant Human ITIH1 Protein, His-tagged

• Cat.No.: ITIH1-19H
• Product Overview: Recombinant Human ITIH1 Protein (Ser507~Asp819) was expressed in E. coli with N-terminal His Tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 507-819 a.a.
• Description: This gene encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 38.5kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 90%
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.

Gene Information

• Gene Name: ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 [ Homo sapiens (human) ]
• Official Symbol: ITIH1
• Synonyms: H1P; ITIH; SHAP; IATIH; IGHEP1; ITI-HC1
• Gene ID: 3697
• mRNA Refseq: NM_002215.3
• Protein Refseq: NP_002206.2
• MIM: 147270
• UniProt ID: P19827