Recombinant Human ITGB7 Protein (Met1-Leu798), C-MYC/DDK tagged

• Cat.No.: ITGB7-4330H
• Product Overview: Recombinant human ITGB7 (Met1-Leu798) fused with the C-terminal MYC/DDK tag was expressed in Mammalian cells.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Myc&DDK
• ProteinLength: Met1-Leu798
• Description: Integrin alpha E beta 7 consist of two major subunits: Integrin alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) and Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. Integrin alpha E beta 7 (CD103) is expressed mainly by cells of the T lymphocyte lineage within mucosal tissues. This is a strikingly narrow pattern of expression compared with that of other integrins. Lymphocytes expressing alpha E beta 7 are abundant in the gut and comprise a major part of the total T cell complement of the body. The effectiveness of lung transplantation is marred by the relatively high incidence of rejection. The lung normally contains a large population of lymphocytes in contact with the airway epithelium, a proportion of which expresses the mucosal integrin, alpha (E) (CD103) beta (7) . This integrin is not a homing receptor, but is thought to retain lymphocytes at the epithelial surface.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 87.78 kDa
• Endotoxin: < 1.0 EU/μg of the protein as determined by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: ITGB7 integrin, beta 7 [ Homo sapiens (human) ]
• Official Symbol: ITGB7
• Synonyms: ITGB7; integrin, beta 7; integrin beta-7; integrin beta 7 subunit; gut homing receptor beta subunit
• Gene ID: 3695
• mRNA Refseq: NM_000889
• Protein Refseq: NP_000880
• MIM: 147559
• UniProt ID: P26010