Recombinant Human ITGA1

• Cat.No.: ITGA1-29494TH
• Product Overview: Recombinant fragment of Human Integrin alpha 1 with proprietary tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Protein Length: 109 amino acids
• Description: This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
• Molecular Weight: 37.620kDa inclusive of tags
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: QFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTI
• Sequence Similarities: Belongs to the integrin alpha chain family.Contains 7 FG-GAP repeats.Contains 1 VWFA domain.

Gene Information

• Gene Name: ITGA1 integrin, alpha 1 [ Homo sapiens ]
• Official Symbol: ITGA1
• Synonyms: ITGA1; integrin, alpha 1; integrin alpha-1; CD49a; VLA1
• Gene ID: 3672
• mRNA Refseq: NM_181501
• Protein Refseq: NP_852478
• MIM: 192968
• Uniprot ID: P56199
• Chromosome Location: 5q11.1
• Pathway: Arf6 trafficking events, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; CHL1 interactions, organism-specific biosystem
• Function: collagen binding; integrin binding; protein binding; protein heterodimerization activity; receptor activity