Recombinant Human Isopentenyl-Diphosphate Delta Isomerase 2, His-tagged

• Cat.No.: IDI2-1710H
• Product Overview: Recombinant human IDI2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: IDI2, also known as isopentenyl-diphosphate delta-isomerase 2, belongs to the IPP isomerase type 1 family. IDI2 catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
• Concentration: 0.5 mg/ml
• Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 1mM DTT and 0.1mM PMSF.
• Purity: > 80% by SDS - PAGE
• Sequence: 1-227 amino acids: MGSSHHHHHH SSGLVPRGSH MSDINLDWVD RRQLQRLEEM LIVVDENDKV IGADTKRNCH LNENIEKGLL HRAFSVVLFN TKNRILIQQR SDTKVTFPGY FTDSCSSHPL YNPAELEEKD AIGVRRAAQR RLQAELGIPG EQISPEDIVF MTIYHHKAKS DRIWGEHEIC YLLLVRKNVT LNPDPSETKS ILYLSQEELW ELLEREARGE VKVTP
• Molecular Mass: 28.9 kDa (247aa), confirmed by MALDI-TOF
• Applications: SDS-PAGE
• Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: IDI2 isopentenyl-diphosphate delta isomerase 2 [ Homo sapiens ]
• Official Symbol: IDI2
• Synonyms: IDI2; isopentenyl-diphosphate Delta-isomerase 2; IPP isomerase 2; OTTHUMP00000018952; isopentenyl pyrophosphate isomerase 2; diphosphate dimethylallyl diphosphate isomerase 2; EC=5.3.3.2
• Gene ID: 91734
• mRNA Refseq: NM_033261
• Protein Refseq: NP_150286
• UniProt ID: Q9BXS1
• Chromosome Location: 10p15.3
• Pathway: C5 isoprenoid biosynthesis; Cholesterol biosynthesis; Metabolic pathways; Metabolism of lipids and lipoproteins; Terpenoid backbone biosynthesis; mevalonate pathway I; superpathway of cholesterol biosynthesis; superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate); trans,trans-farnesyl diphosphate biosynthesis
• Function: hydrolase activity; isomerase activity; metal ion binding; isopentenyl-diphosphate delta-isomerase activity