Recombinant Human INTS1 Protein, MYC/DDK-tagged

• Cat.No.: INTS1-2445H
• Product Overview: Recombinant Human INTS1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 244.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: INTS1 integrator complex subunit 1 [ Homo sapiens ]
• Official Symbol: INTS1
• Synonyms: INT1; NET28
• Gene ID: 26173
• mRNA Refseq: NM_001080453.2
• Protein Refseq: NP_001073922.2
• MIM: 611345
• UniProt ID: Q8N201