Recombinant Human Interleukin 8
Cat.No. : | IL8-130H |
Product Overview : | Recombinant Human interleukin 8 encoding the human IL-8 protein sequence (containing the signal peptide sequence, and the mature IL-8 sequence) and was expressed in modifiedhuman 293 cells. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | HEK293 |
Tag : | Non |
Description : | IL-8 is a member of the chemokine family. Chemokines are small secreted molecules containing 4 conserved cysteine residues and 2 disulfide linkages. IL-8 is a member of the CXC family of chemokines and is also known as CXCL8. IL-8 is predominantly produced by monocytes, T cells, NK cells and neutrophils and its expression is induced by IL-1 and TNF, as well as bacterial and viral products. |
Amino Acid Sequence : | SAKELRCQCIKTYSKP FH PKFIK ELRV IESGPHCANTE IIVKLSDGRELC LDP KEN WVQR VVEKFLKRAENS. |
Molecular Mass : | IL-8 migrates as a band at approximately 6-8 kDa in SDS-PAGE. This compares with unmodified IL-8 that has a predicted molecular mass of 8.4 kDa. |
PI : | IL-8 has a predicted pI of 9.02. |
Purity : | >95%, as determined by SDS-PAGE and visualized by silver stain. |
Formulation : | When reconstituted in 0.5 ml sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose. |
Reconstitution : | It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial. |
Storage : | Lyophilized products should be stored at 2 to 8°C. Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended. |
Gene Name | IL8 interleukin 8 [ Homo sapiens ] |
Synonyms | IL8; interleukin 8; CXCL8; GCP-1; GCP1; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; T cell chemotactic factor; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; emoctakin; granulocyte chemotactic protein 1; lymphocyte-derived neutrophil-activating factor; monocyte-derived neutrophil chemotactic factor; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; K60; T-cell chemotactic factor; b-ENAP; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; Neutrophil-activating protein 1 |
Gene ID | 3576 |
mRNA Refseq | NM_000584 |
Protein Refseq | NP_000575 |
MIM | 146930 |
UniProt ID | P10145 |
Chromosome Location | 4q13-q21 |
Pathway | Cytokine-cytokine receptor interaction; Pathways in cancer; Toll-like receptor signaling pathway; Bladder cancer; Chemokine signaling pathway; Epithelial cell signaling in Helicobacter pylori infection; RIG-I-like receptor signaling pathway; Signaling by GPCR |
Function | interleukin-4 receptor activity; cytokine activity; chemokine activity; protein binding |
◆ Recombinant Proteins | ||
CENPBD1-4347H | Recombinant Human CENPBD1 Protein, GST-tagged | +Inquiry |
RGS5-3876R | Recombinant Rhesus monkey RGS5 Protein, His-tagged | +Inquiry |
PIP4K2A-0265H | Recombinant Human PIP4K2A Protein (A2-T406), His tagged | +Inquiry |
NUDT16-2326H | Recombinant Human NUDT16 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
PGA4-1278H | Recombinant Human PGA4 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Native Proteins | ||
C2-98H | Active Native Human C2 Protein | +Inquiry |
Apotransferrin-39H | Native Human Apotransferrin | +Inquiry |
FG-116H | Native Human Fibrinogen | +Inquiry |
C1R-96H | Active Native Human C1r Enzyme | +Inquiry |
IgG-332S | Native Swine IgG | +Inquiry |
◆ Cell & Tissue Lysates | ||
CRLF1-404HCL | Recombinant Human CRLF1 cell lysate | +Inquiry |
TJAP1-1056HCL | Recombinant Human TJAP1 293 Cell Lysate | +Inquiry |
Heart-137R | Rat Heart Tissue Lysate | +Inquiry |
OTUD7B-3513HCL | Recombinant Human OTUD7B 293 Cell Lysate | +Inquiry |
ACO1-510HCL | Recombinant Human ACO1 cell lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All IL8 Products
Required fields are marked with *
My Review for All IL8 Products
Required fields are marked with *
0
Inquiry Basket