Recombinant Human Interleukin 4 Receptor, His-tagged

• Cat.No.: IL4R-284H
• Product Overview: Recombinant Human IL-4R alpha extracellular domain(C-terminus fused with 6xHis) produced in mammalian cells contains 212 amino acids with predicted MW 24.42 KD. It contains 7 cysteines as well as 6 N-link glycosylation sites with MW increase up to 30 KD.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: His
• Description: human IL-4 receptor (heterodimer of an alpha and a common gamma chain) may represent a regulatory molecule specific for IL-4-dependent immune response. Well-documented antibodies are commercially available to characterize its immunoreactivity.
• Purity: >90%.
• Recommended Storage Temperature: -70°C.

Gene Information

• Gene Name: IL4R interleukin 4 receptor [ Homo sapiens ]
• Synonyms: IL4R; interleukin 4 receptor; CD124; IL4RA; interleukin 4 receptor alpha chain; OTTHUMP00000122506; interleukin-4 receptor alpha chain;CD_antigen;IL-4R-alpha; Soluble interleukin-4 receptor alpha chain; sIL4Ralpha/prot; IL-4-binding protein; IL4-BP
• Gene ID: 3566
• mRNA Refseq: NM_000418
• Protein Refseq: NP_000409
• MIM: 147781
• UniProt ID: P24394
• Chromosome Location: 16p12.1-p11.2
• Pathway: Cytokine-cytokine receptor interaction; Endocytosis; Hematopoietic cell lineage; Jak-STAT signaling pathway
• Function: interleukin-4 receptor activity; receptor activity; protein binding; receptor signaling protein activity