Recombinant Human Interleukin 1 Family, Member 7, His-tagged

• Cat.No.: IL1F7-159H
• Product Overview: Recombinant Human IL1F7 encoding the human IL1F7 Isoform B (Va^l46–Asp²¹⁸) was expressed inE.coli. It was recombined with a Hexa-his N-Terminus and purified by Nicolumn.MW=19.3 KD.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 46-218 a.a.
• Description: IL-1F7 binds to interleukin-18 receptor (IL-18R) receptor but not to IL-1 receptor. That Could be a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis. IL1F7 isoform B were expressed in testis, colon, placenta, lung and lymph node. It was reported that isoform B were expressed in kidney.
• Sequence: Human IL1F7 isoform B (Va^l46–Asp²¹⁸)46 VHTSPKVKNL NPKKFSIHDQ DHKVLVLDSG NLIAVPDKNY IRPEIFFALA SSLSSASAEK GSPILLGVSK GEFCLYCDKD KGQSHPSLQL KKEKLMKLAA QKESARRPFI FYRAQVGSWN MLESAAHPGW FICTSCNCNE PVGVTDKFEN RKHIEFSFQP VCKAEMSPSE VSD 216
• Formulation: Lyophilized 100μg humanIL1F7 in 50μl of TBS (20mM Tris, 50mM NaCl, pH8.0). Carry free.
• Purity: >95% by SDS gel.
• Application: Cell biology.
• Reconstitution: Add 500μl deionized water to the vial to prepare a working stock solution at 200μg/mL . Allow to set at least 30 minutes at 4℃, mix well.
• Storage: Store lyophilized protein at -20℃ or -70℃. Lyophilized protein is stable for up to 6 months from date of receipt at -20℃ to -70℃. Upon reconstitution, this protein can be stored at -20℃ for a few weeks or at -70℃ in a manual defrost freezer for long term storage (six months). Aliquot reconstituted protein to avoid repeated freezing / thawing cycles.

Gene Information

• Gene Name: IL1F7 interleukin 1 family, member 7 (zeta) [ Homo sapiens ]
• Synonyms: IL1F7; interleukin 1 family, member 7 (zeta); FIL1; FIL1Z; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1; FIL1(ZETA); interleukin 1 family, member 7; IL-1X protein; interleukin 1, zeta; interleukin-1 homolog 4; interleukin-1 superfamily z; interleukin 1 family member 7; interleukin-1-related protein; IL-1F7b (IL-1H4, IL-1H, IL-1RP1); IL1F7 (canonical product IL-1F7b); Interleukin-1 family member 7; Interleukin-1 zeta; IL-1 zeta; FIL1 zeta; Interleukin-1 homolog 4; Interleukin-1-related protein; IL-1X protein
• Gene ID: 27178
• mRNA Refseq: NM_014439
• Protein Refseq: NP_055254
• MIM: 605510
• UniProt ID: Q9NZH6
• Chromosome Location: 2q12-q14.1