Cat. No. :	IFNG-94H
Description :	Interferon gamma, also known as IFN-gamma, Immune interferon and IFNG, is a secreted protein which belongs to the type II (or gamma) interferon family. IFN-gamma / IFNG is produced by lymphocytes and activated by specific antigens or mitogens. IFN-gamma / IFNG, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Source :	CHO Cells.
Molecular Mass :	The secreted recombinant human γ-IFN consists of 143 amino acids and has a predicted molecular mass of 16.7 kDa. γ-IFN migrates as two bands with apparent molecular mass of 21&25 kDa probably due to different glycosylation.
Predicted N Terminal :	Gln 24.
Purity :	> 92 %.
Formulation :	Lyophilized from sterile PBS, pH 7.4.
Endotoxin :	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution :	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Storage And Stability :	Samples are stable for up to twelve months from date of receipt at -70⁰C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Tag :	Non
Protein length :	1-166 a.a.

Gene Name	IFNG interferon, gamma [ Homo sapiens ]
Synonyms	IFG; IFI;Immune interferon, type II interferon; T cell interferon; MAF; IFN-gamma; Interferongamma; Interferon gamma precursor; interferon gamma; IFNG; interferon, gamma
Gene ID	3458
mRNA Refseq	NM_000619
Protein Refseq	NP_000610
MIM	147570
UniProt ID	P01579
Chromosome Location	12q14
Pathway	Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; Regulation of autophagy; T cell receptor signaling pathway; TGF-beta signaling pathway; Type I diabetes mellitus
Function	cytokine activity; interferon-gamma receptor binding