Recombinant Human Interferon Gamma

• Cat.No.: IFNG-94H
• Product Overview: Recombinant HumanIFNG protein (Met 1 - Gln 166) was expressed inCHO Cells.

Specification

• Species: Human
• Source: CHO
• Tag: Non
• Protein Length: 1-166 a.a.
• Description: Interferon gamma, also known as IFN-gamma, Immune interferon and IFNG, is a secreted protein which belongs to the type II (or gamma) interferon family. IFN-gamma / IFNG is produced by lymphocytes and activated by specific antigens or mitogens. IFN-gamma / IFNG, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
• Molecular Mass: The secreted recombinant human γ-IFN consists of 143 amino acids and has a predicted molecular mass of 16.7 kDa. γ-IFN migrates as two bands with apparent molecular mass of 21&25 kDa probably due to different glycosylation.
• Predicted N Terminal: Gln 24.
• Purity: > 92 %.
• Formulation: Lyophilized from sterile PBS, pH 7.4.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Storage And Stability: Samples are stable for up to twelve months from date of receipt at -70⁰C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: IFNG interferon, gamma [ Homo sapiens ]
• Synonyms: IFG; IFI;Immune interferon, type II interferon; T cell interferon; MAF; IFN-gamma; Interferongamma; Interferon gamma precursor; interferon gamma; IFNG; interferon, gamma
• Gene ID: 3458
• mRNA Refseq: NM_000619
• Protein Refseq: NP_000610
• MIM: 147570
• UniProt ID: P01579
• Chromosome Location: 12q14
• Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; Regulation of autophagy; T cell receptor signaling pathway; TGF-beta signaling pathway; Type I diabetes mellitus
• Function: cytokine activity; interferon-gamma receptor binding