Recombinant Human Intercellular Adhesion Molecule-1, His-tagged

• Cat.No.: ICAM1-278H
• Product Overview: Recombinant Human ICAM-1 comprises a 455 amino acid fragment (28-483) corresponding to the mature extracellular domain of the ICAM protein and is expressed in E. coli with an amino-terminal hexahistidine tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 28-483 a.a.
• Description: ICAM-1 is a single chain membrane glycoprotein expressed on the surface of a variety of nonhaematopoietic and haematopoietic cell types and has roles in signal transduction, cell signalling and lymphocyte adhesion. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory conditions.
• Purity: >95% by SDS-PAGE
• Applications: ELISA, Western Blot
• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Gene Information

• Gene Name: ICAM1 intercellular adhesion molecule 1 [ Homo sapiens ]
• Synonyms: Intercellular adhesion molecule; BB2; CD54; cell surface glycoprotein P3.58; human rhinovirus receptor; major group rhinovirus receptor; ICAM1; P3.58; intercellular adhesion molecule 1; ICAM-1; CD54 antigen; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor.
• Gene ID: 3383
• mRNA Refseq: NM_000201
• Protein Refseq: NP_000192
• MIM: 147840
• UniProt ID: P05362
• Chromosome Location: 19p13.3-p13.2
• Pathway: Cell adhesion molecules (CAMs); Leukocyte transendothelial migration; Natural killer cell mediated cytotoxicity; Integrin cell surface interactions; Signaling in Immune system
• Function: integrin binding; protein binding; transmembrane receptor activity