Recombinant Human Inhibin, Beta A, His-tagged

• Cat.No.: INHBA-5059H
• Product Overview: Recombinant human INHBA was expressed in Nicotiana benthamiana and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: Activin A is a TGF beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF beta antagonist, Follistatin.
• Concentration: 50 ng/ul
• Form: Lyophilized from 50mM Tris HCl at pH 7.4.
• Purity: > 97% by SDS - PAGE gel
• Sequence: HHHHHHGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
• Molecular Mass: 13.7 kDa beta A single chain, containing 116 amino residues
• Applications: Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions.
• Endotoxin Levels: <0.04 EU/ug protein (LAL method)
• Storage: Aliquot and store at -20 deg C. Avoid repeated freeze/thaw Cycles

Gene Information

• Gene Name: INHBA inhibin, beta A [ Homo sapiens ]
• Official Symbol: INHBA
• Synonyms: A-inhibin subunit; inhibin alpha subunit; inhibin, alpha; INHA; Inhibin A; Inhibin isoform A
• Gene ID: 3624
• mRNA Refseq: NM_002192
• Protein Refseq: NP_002183
• MIM: 147290
• UniProt ID: P08476
• Chromosome Location: 7p15-p13
• Pathway: ALK1 signaling events; Cytokine-cytokine receptor interaction; Senescence and Autophagy; TGF Beta Signaling Pathway
• Function: cytokine activity; follistatin binding; growth factor activity; hormone activity; identical protein binding; signal transducer activity