Recombinant Human INHBA Protein

• Cat.No.: INHBA-552H
• Product Overview: Recombinant human INHBA protein without tag was expressed in HEK293.

Specification

• Description: This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients.
• Source: HEK293
• Species: Human
• Form: Lyophilized
• Molecular Mass: 13 kDa (mature-form) & 32 kDa (pro-form)
• Protein length: 426
• AA Sequence: MPLLWLRGFLLASCWIIVRSSPTPG SEGHSAAPDCPSCALAALPKDVPNS QPEMVEAVKKHILNMLHLKKRPDVT QPVPKAALLNAIRKLHVGKVGENGY VEIEDDIGRRAEMNELMEQTSEIIT FAESGTARKTLHFEISKEGSDLSVV ERAEVWLFLKVPKANRTRTKVTIRL FQQQKHPQGSLDTGEEAEEVGLKGE RSELLLSEKVVDARKSTWHVFPVSS SIQRLLDQGKSSLDVRIACEQCQES GASLVLLGKKKKKEEEGEGKKKGGG EGGAGADEEKEQSHRPFLMLQARQS EDHPHRRRRRGLECDGKVNICCKKQ FFVSFKDIGWNDWIIAPSGYHANYC EGECPSHIAGTSGSSLSFHSTVINH YRMRGHSPFANLKSCCVPTKLRPMS MLYYDDGQNIIKKDIQNMIVEECGC S
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5)
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: INHBA inhibin, beta A [ Homo sapiens (human) ]
• Official Symbol: INHBA
• Synonyms: INHBA; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); inhibin beta A chain; Inhibin, beta-1; activin beta-A chain; FSH-releasing protein; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; EDF; FRP
• Gene ID: 3624
• mRNA Refseq: NM_002192
• Protein Refseq: NP_002183
• MIM: 147290
• UniProt ID: P08476

Reviews

12/15/2018

The value derived from the product's usage made the investment worthwhile, considering the insights acquired.

08/17/2018

Its reliability over time reduced the need for frequent reordering, saving both time and resources.

02/24/2017

The product’s biocompatibility with various cell types and organisms made it versatile for a wide range of applications.

Q&As

In which tissues is INHBA predominantly expressed?

INHBA is often expressed in the ovaries and testes.

What is the role of INHBA in the body?

INHBA is involved in the regulation of reproductive processes and cell growth.

What is the molecular weight of the INHBA protein?

The molecular weight is approximately 45 kDa.

Which genes code for the production of INHBA?

INHBA is encoded by the INHBA gene.

Is INHBA associated with any diseases?

Mutations in the INHBA gene can be linked to certain reproductive disorders.

What is the full name of the INHBA protein?

The full name is “Inhibin subunit beta A.”

Does INHBA have any known protein interactions?

Yes, INHBA can interact with other proteins involved in cell signaling pathways.