Recombinant Human INHA/INHBA protein, His-tagged

• Cat.No.: INHA/INHBA-32H
• Product Overview: Inhibin-Alpha Human Recombinant produced in E.Coli is a non-glycosylated, polypeptide chain containing 264 amino acids comprising of both A and B chains, having a molecular mass of 33.5 kDa.The Inhibin-Alpha is fused with an amino-terminal hexahistidine tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Alpha chain: 233-366 aa Beta Chain: 293-406 aa
• Description: Inhibins are dimeric peptide hormones produced by female ovarian granulose cells and male Sertoli cells as well as a variety of other tissues. Inhibins have two isoforms, A and B, with the same alpha subunit but different beta subunits. Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits.Inhibins are thought to inhibit the production of follicle-stimulating hormone (FSH) by the pituitary gland. In addition, Inhibins are also thought to play a role in the control of gametogenesis, and embryonic and fetal development.
• Form: Inhibin-A alpha chain is supplied in 1x PBS and 50% glycerol.
• Molecular Mass: 33.5 kDa
• AA Sequence: Alpha chain:STPLMSWPWSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIP PNLSLPVPGAPPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCACI.Beta Chain:GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS.
• Purity: Greater than 95.0% as determined by SDS-PAGE analysis.
• Storage: Store at 4 centigrade if entire vial will be used within 2-4 weeks.Store, frozen at -20 centigrade for longer periods of time. Please avoid freeze thaw cycles.

Gene Information

• Gene Name: INHA inhibin, alpha [ Homo sapiens ]
• Official Symbol: INHA
• Synonyms: INHA; inhibin, alpha; inhibin alpha chain; A-inhibin subunit
• Gene ID: 3623
• mRNA Refseq: NM_002191
• Protein Refseq: NP_002182
• MIM: 147380
• UniProt ID: P05111
• Chromosome Location: 2q33-qter
• Pathway: Glycoprotein hormones, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Ovarian Infertility Genes, organism-specific biosystem; Peptide hormone biosynthesis, organism-specific biosystem
• Function: cytokine activity; growth factor activity; hormone activity; inhibin beta-A binding; protein binding; contributes_to protein binding; protein heterodimerization activity; receptor binding