Recombinant Human INHA, His-tagged

• Cat.No.: INHA-8291H
• Product Overview: Recombinant human INHA protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Inhibins are dimeric peptide hormones produced by female ovarian granulose cells and male Sertoli cells as well as a variety of other tissues. Inhibins have two isoforms, A and B, with the same alpha subunit but different beta subunits. Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits. Inhibins are thought to inhibit the production of follicle-stimulating hormone (FSH) by the pituitary gland. In addition, Inhibins are also thought to play a role in the control of gametogenesis, and embryonic and foetal development. recombinant Inhibin A is a 264 amino acid, single chain protein, comprising the mature inhibin α and the mature βA chain (α-βA). The protein is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Applications: ELISA, Western Blot

Gene Information

• Gene Name: INHA inhibin, alpha [ Homo sapiens ]
• Official Symbol: INHA
• Synonyms: INHA; inhibin, alpha; inhibin alpha chain; A-inhibin subunit
• Gene ID: 3623
• mRNA Refseq: NM_002191
• Protein Refseq: NP_002182
• MIM: 147380
• UniProt ID: P05111
• Chromosome Location: 2q33-qter
• Pathway: Glycoprotein hormones, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Ovarian Infertility Genes, organism-specific biosystem; Peptide hormone biosynthesis, organism-specific biosystem
• Function: cytokine activity; growth factor activity; hormone activity; inhibin beta-A binding; protein binding; contributes_to protein binding; protein heterodimerization activity; receptor binding