Recombinant Human IL3RA Protein, C-Fc-Avi tagged, Biotinylated

• Cat.No.: IL3RA-06H
• Product Overview: Biotinylated Recombinant Human Interleukin-3 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Thr19-Arg305 is expressed with a Fc, Avi tag at the C-terminus.

Specification

• Species: Human
• Source: Human Cells
• Tag: Avi&Fc
• Protein Length: Thr19-Arg305
• Description: CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF receptors. CD123 stimulates the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as various lineage?committed cells. CD123 is a heterodimer consisting of an alpha and a beta subunit. The alpha subunit alone binds IL?3 with low affinity. The beta subunit does not bind IL-3 by itself but is required for the high-affinity binding of IL-3 to the heterodimeric receptor complex.
• Endotoxin: Less than 0.1 ng/μg (1 EU/μg)
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Shipping: Ambient

Gene Information

• Gene Name: IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens (human) ]
• Official Symbol: IL3RA
• Synonyms: Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunitalpha; IL-3R-alpha; IL-3RA; CD123
• Gene ID: 3563
• mRNA Refseq: NM_002183
• Protein Refseq: NP_002174
• MIM: 308385
• UniProt ID: P26951