Recombinant Human IL34 Protein, His-tagged

• Cat.No.: IL34-001H
• Product Overview: Recombinant human IL34 (21-242aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 21-242 a.a.
• Description: IL34, also known as interleukin-34 isoform 1, is a secreted cytokine. This protein is expressed in a variety of tissues richest in the spleen and stimulates the proliferation of monocytes. In a functional study, IL-34, such as CSF-1, another ligand for CSF-1R, stimulated phosphorylation of extracellular signal-regulated kinase-1 and -2 (ERK1 / 2) in human monocytes. In addition, it promoted the formation of macrophage precursor colonization units-macrophages (CFU-M) in human bone marrow cultures.
• Form: Liquid
• Molecular Mass: 26.3 kDa
• N-terminal Sequence Analysis: Ala
• Endotoxin: < 1.0 EU per 1 μg of protein (determined by LAL method)
• Purity: > 90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/mL (determined by Absorbance at 280nm)
• Storage Buffer: In 20mM Tris-Hcl buffer (pH 8.5) containing 1mM DTT, 0.15M NaCl, 01mM PMSF, 1mM EDTA, 30% glycerol.
• Warning: For research use only. This product is not intended or approved for human, diagnostics or veterin
• AA Sequence: ADPNEPLEMWPLTQNEECTVTGFLRDKLQYRSRLQYMKHYFPINYKISVPYEGVFRIANVTRLQRAQVSERELRYLWVLVSLSATESVQDVLLEGHPSWKYLQEVQTLLLNVQQGLTDVEVSPKVESVLSLLNAPGPNLKLVRPKALLDNCFRVMELLYCSCCKQSSVLNWQDCEVPSPQSCSPEPSLQYAATQLYPPPPWSPSSPPHSTGSVRPVRAQGEGLLPHHHHHH

Gene Information

• Gene Name: IL34 interleukin 34 [ Homo sapiens (human) ]
• Official Symbol: IL34
• Synonyms: IL34; interleukin 34; IL-34; C16orf77; interleukin-34
• Gene ID: 146433
• mRNA Refseq: NM_152456
• Protein Refseq: NP_689669
• MIM: 612081
• UniProt ID: Q6ZMJ4