Il34
-
Official Full Name
interleukin 34 -
Overview
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008] -
Synonyms
IL34;interleukin 34;IL-34;C16orf77;interleukin-34
Recombinant Proteins
- Human
- Mouse
- Rat
- Rhesus macaque
- Zebrafish
- E.coli
- Human Cell
- Insect Cell
- Mammalian cells
- CHO
- HEK293
- Mammalian Cell
- Yeast
- Baculovirus-Insect cells
- HEK293F
- Human Cells
- HEK293T
- GST
- His
- Fc
- Myc&DDK
- Non
- His&Avi
- His&Fc
- His&Fc&Avi
Involved Pathway
Il34 involved in several pathways and played different roles in them. We selected most pathways Il34 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Il34 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Il34 has several biochemical functions, for example, cytokine activity,growth factor activity,macrophage colony-stimulating factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il34 itself. We selected most functions Il34 had, and list some proteins which have the same functions with Il34. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | FASLG,BMP15,GRN,IFNA17,CMTM3,VEGFA,CSF3,IL22,IL11,Cxcl15 |
| macrophage colony-stimulating factor receptor binding | CSF1,STAP1 |
| growth factor activity | AMBN,FGF11A,BMP15,FGF10B,LEFTY2,GDF6,BMP5,INHBAB,GDF10B,BMP3 |
Interacting Protein
Il34 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il34 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il34.
ATXN1
Resources
Research Area
Multiple Sclerosis and Myelin Related MoleculesOther Interleukins & Receptors
Macrophage Markers
Related Services
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References
