Recombinant Human IL2RB Protein

• Cat.No.: IL2RB-5196H
• Product Overview: Human IL2RB (P14784, Ala 27- Asp 239) partial recombinant protein expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Non
• Description: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq
• Form: Lyophilized
• Molecular Mass: 42 kDa
• Endotoxin: < 0.1 ng/μg (1 EU/μg)
• Purity: > 90% by SDS-PAGE and HPLC
• Applications: SDS-PAGE
• Storage: Store at -20 centigrade on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4 centigrade for 1 month or store at -20 centigrade for 12 months. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: Lyophilized PBS, pH 7.2

Gene Information

• Gene Name: IL2RB interleukin 2 receptor, beta [ Homo sapiens ]
• Official Symbol: IL2RB
• Synonyms: IL2RB; interleukin 2 receptor, beta; IL15RB, interleukin 15 receptor, beta; interleukin-2 receptor subunit beta; CD122; p75; IL-2RB; CD122 antigen; IL-2R subunit beta; IL-2 receptor subunit beta; interleukin 15 receptor, beta; high affinity IL-2 receptor beta subunit; high affinity IL-2 receptor subunit beta; IL15RB; P70-75
• Gene ID: 3560
• mRNA Refseq: NM_000878
• Protein Refseq: NP_000869
• MIM: 146710
• UniProt ID: P14784