Recombinant Human IL28A
Cat.No. : | IL28A-29785TH |
Product Overview : | Recombinant Human IL28A, a 19.6 kDa protein containing 174 amino acid residues. |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Description : | This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). |
Biological activity : | Biological activity of IL28A-29785TH is determined by its ability to activate STAT phosphorylation in an ISRE Luciferase Reporter Assay using human colon carcinoma COLO205 cells. |
Form : | Lyophilised |
Storage : | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. |
Sequences of amino acids : | PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV |
Sequence Similarities : | Belongs to the IL-28/IL-29 family. |
Gene Name | IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens ] |
Official Symbol | IL28A |
Synonyms | IL28A; interleukin 28A (interferon, lambda 2); interleukin 28A; interleukin-28A; IFNL2; IL 28A; |
Gene ID | 282616 |
mRNA Refseq | NM_172138 |
Protein Refseq | NP_742150 |
MIM | 607401 |
Uniprot ID | Q8IZJ0 |
Chromosome Location | 19q13.13 |
Pathway | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
Function | cytokine activity; |
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Il28a-229M | Recombinant Mouse Interleukin 28a | +Inquiry |
IL28A-136H | Active Recombinant Human IL28A protein | +Inquiry |
Il28a-5202M | Active Recombinant Mouse Il28a Protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
IL28A-5229HCL | Recombinant Human IL28A 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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