Recombinant Human IL27 Protein (Phe29-Pro243), C-His tagged

• Cat.No.: IL27-3776H
• Product Overview: Recombinant human IL27 (Phe29-Pro243) fused with the C-terminal His tag was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A) . It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR) .
• Source: Mammalian cells
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 23.76 kDa
• Protein length: Phe29-Pro243
• Endotoxin: < 1.0 EU/μg of the protein as determined by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: IL27 interleukin 27 [ Homo sapiens (human) ]
• Official Symbol: IL27
• Synonyms: interleukin-27 subunit alpha; IL27; interleukin 27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28; IL-27 p28 subunit; IL-27 subunit alpha; IL-27-A; IL27-A; interleukin-30
• Gene ID: 246778
• mRNA Refseq: NM_145659
• Protein Refseq: NP_663634
• MIM: 608273
• UniProt ID: Q8NEV9