Recombinant Human IL23R protein, mFc-tagged

• Cat.No.: IL23R-614H
• Product Overview: Recombinant Human IL23R protein(Q5VWK5-1)(Gly24-Gly355), fused with C-terminal mFc tag, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: mFc
• Protein Length: Gly24-Gly355
• Tag: C-mFc
• Form: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
• Bio-activity: Immobilized Biotinylated Human IL-23 alpha&IL-12 beta, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Human IL-23R, mFc Tag with the EC50 of 11.1ng/ml determined by ELISA.
• Molecular Mass: The protein has a predicted MW of 63.7 kDa. Due to glycosylation, the protein migrates to 80-115 kDa based on Tris-Bis PAGE result.
• Endotoxin: Less than 1EU per μg by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
• Storage: Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
• Reconstitution: Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Gene Information

• Gene Name: IL23R interleukin 23 receptor [ Homo sapiens ]
• Official Symbol: IL23R
• Synonyms: IL23R; interleukin 23 receptor; interleukin-23 receptor; IL 23R; IL-23 receptor
• Gene ID: 149233
• mRNA Refseq: NM_144701
• Protein Refseq: NP_653302
• MIM: 607562
• UniProt ID: Q5VWK5