Recombinant Human IL1RL2 protein, Fc-tagged
Cat.No. : | IL1RL2-318H |
Product Overview : | Recombinant Human IL1RL2 protein (Asp20-Arg335), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
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Species : | Human |
Source : | HEK293 |
Tag : | Fc |
Protein Length : | 316 |
Description : | The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain. |
Form : | Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 62.4 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name | IL1RL2 |
Official Symbol | IL1RL2 |
Synonyms | IL1RL2; interleukin 1 receptor-like 2; interleukin-1 receptor-like 2; IL1R rp2; IL1RRP2; IL-1Rrp2; interleukin-1 receptor-related protein 2; IL1R-rp2 |
Gene ID | 8808 |
mRNA Refseq | NM_003854 |
Protein Refseq | NP_003845 |
MIM | 604512 |
UniProt ID | Q9HB29 |
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Not For Human Consumption!
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