Recombinant Human IL1R1 protein, His-tagged

• Cat.No.: IL1R1-552H
• Product Overview: Recombinant Human IL1R1 (P14778) aa. (Asp21~Ile109) fused with His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 11.6kDa; Accurate Molecular Mass: 14kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Asp21~Ile109
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: Isoelectric point is 7.8.
• Applications: Cell culture; Activity Assays; In vivo assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: 20mM Tris, 150mM NaCl,pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Information

• Gene Name: IL1R1 interleukin 1 receptor type 1 [ Homo sapiens (human) ]
• Official Symbol: IL1R1
• Synonyms: IL1R1; P80; IL1R; IL1RA; CD121A; D2S1473; IL-1R-alpha; interleukin-1 receptor type 1; CD121 antigen-like family member A; IL-1R-1; IL-1RT-1; IL-1RT1; interleukin 1 receptor alpha, type I; interleukin-1 receptor alpha; interleukin-1 receptor type I
• Gene ID: 3554
• mRNA Refseq: NM_000877.3
• Protein Refseq: NP_000868.1
• UniProt ID: P14778