Recombinant Human IL18BP Protein, Thr31-Gly194, C-His-Avi tagged, Biotinylated

Cat.No. : IL18BP-135H
Product Overview : Recombinant human IL-18BP-C-His-Avi protein was developed from HEK293 and has a target region of C-His-Avi.
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Species : Human
Source : HEK293
Tag : Avi&His
Protein Length : Thr31-Gly194
Description : The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Conjugation/Label : Biotin
Form : Lyophilised
Endotoxin : Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg).
Notes : FOR RESEARCH USE ONLY (RUO).
Storage : The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade.
Storage Buffer : Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM
Gene Name IL18BP interleukin 18 binding protein [ Homo sapiens (human) ]
Official Symbol IL18BP
Synonyms IL18BP; interleukin 18 binding protein; interleukin-18-binding protein; IL18BPa; MC51L 53L 54L homolog gene product; IL-18BP; tadekinig-alfa; MC51L-53L-54L homolog gene product;
Gene ID 10068
mRNA Refseq NM_001039659
Protein Refseq NP_001034748
MIM 604113
UniProt ID O95998

Not For Human Consumption!

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