Recombinant Human IKBKE Protein, MYC/DDK-tagged

• Cat.No.: IKBKE-493H
• Product Overview: Recombinant Human IKBKE fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 80.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon [ Homo sapiens ]
• Official Symbol: IKBKE
• Synonyms: IKBKE; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; inhibitor of nuclear factor kappa-B kinase subunit epsilon; IKK i; IKKE; KIAA0151; IKK-epsilon; I-kappa-B kinase epsilon; inducible IkappaB kinase; IKK-related kinase epsilon; inducible I kappa-B kinase; IKKI; IKK-E; IKK-i; MGC125294; MGC125295; MGC125297
• Gene ID: 9641
• mRNA Refseq: NM_014002
• Protein Refseq: NP_054721
• MIM: 605048
• UniProt ID: Q14164