Recombinant Human IGF1R Protein, MYC/DDK-tagged
| Cat.No. : | IGF1R-1392H |
| Product Overview : | Recombinant human IGF1R protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
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| Description : | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc&DDK |
| Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
| Molecular Mass : | 81 kDa |
| Purity : | >50 ug/mL as determined by microplate BCA method |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Gene Name | IGF1R insulin-like growth factor 1 receptor [ Homo sapiens ] |
| Official Symbol | IGF1R |
| Synonyms | CD221; IGFIR; IGFR; JTK13 |
| Gene ID | 3480 |
| mRNA Refseq | NM_000875 |
| Protein Refseq | NP_000866 |
| MIM | 147370 |
| UniProt ID | P08069 |
Not For Human Consumption!
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