Recombinant Human IFNGR1 protein, His & T7-tagged

• Cat.No.: IFNGR1-7038H
• Product Overview: Recombinant Human IFNGR1 aa. (Glu18~Gly245 (Accession # P15260)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29.3kDa
• Protein length: Glu18~Gly245
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.6.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: IFNGR1 interferon gamma receptor 1 [ Homo sapiens (human) ]
• Official Symbol: IFNGR1
• Synonyms: IFNGR1; interferon gamma receptor 1; CD119; IFNGR; IMD27A; IMD27B; AVP, type 2; CD119 antigen; CDw119; IFN-gamma receptor 1; IFN-gamma-R-alpha; IFN-gamma-R1; antiviral protein, type 2; immune interferon receptor 1; interferon-gamma receptor alpha chain
• Gene ID: 3459
• mRNA Refseq: NM_000416.2
• Protein Refseq: NP_000407.1
• UniProt ID: P15260