Recombinant Human IFITM2 Protein, His-GST-tagged

• Cat.No.: IFITM2-001H
• Product Overview: Recombinant Human IFITM2 Protein (1-132 aa (full-length)) with 6xHis-GST tags was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: 1-132
• Description: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
• Molecular Mass: 43.2 kDa
• Purity: >90% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB).
• Applications: ELISA, Western Blot, Antibody Production, Protein array
• Quality Control Test: 10% SDS-PAGE stained with Coomassie Blue (CB), immunoblotting with anti-GST(WB) and peptide fingerprinting by MALDI-TOF mass spectrometry.
• Storage: Store working aliquots at 4 centigrade for up to one week. For extended storage, conserve at −80 centigrade.
• Expiry: 12 months from the date of purchase, if it is properly stored.
• Storage Buffer: 20mM Sodium Phosphate, 0.5M NaCl, 0.15M imidazole, pH 7.4. No preservatives added.
• Shipping: Dry Ice

Gene Information

• Gene Name: IFITM2 interferon induced transmembrane protein 2 [ Homo sapiens (human) ]
• Official Symbol: IFITM2
• Synonyms: IFITM2; interferon induced transmembrane protein 2; 1-8D; DSPA2c; interferon-induced transmembrane protein 2; dispanin subfamily A member 2c; interferon-inducible protein 1-8D
• Gene ID: 10581
• mRNA Refseq: NM_006435
• Protein Refseq: NP_006426
• MIM: 605578
• UniProt ID: Q01629