Recombinant Human IFI16, GST-tagged

• Cat.No.: IFI16-14060H
• Product Overview: Recombinant Human IFI16 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: N-term-353a.a.
• Description: This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: IFI16 interferon, gamma-inducible protein 16 [ Homo sapiens ]
• Official Symbol: IFI16
• Synonyms: IFI16; interferon, gamma-inducible protein 16; gamma-interferon-inducible protein 16; IFNGIP1; PYHIN2; interferon-gamma induced protein IFI 16; interferon-inducible myeloid differentiation transcriptional activator; MGC9466
• Gene ID: 3428
• mRNA Refseq: NM_001206567
• Protein Refseq: NP_001193496
• MIM: 147586
• UniProt ID: Q16666
• Chromosome Location: 1q22
• Pathway: Id Signaling Pathway, organism-specific biosystem; Senescence and Autophagy, organism-specific biosystem
• Function: DNA binding; double-stranded DNA binding; protein binding