Recombinant Human HVCN1 protein, His-tagged

• Cat.No.: HVCN1-1410H
• Product Overview: Recombinant Human HVCN1 protein(NP_001035196.1)(Met1~Val138) was fused to His Tag and expressed in E.coli.

Specification

• Description: This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: His
• Form: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Molecular Mass: 13/14kDa(Analysis of differences refer to the manual)
• Protein length: Met1~Val138
• AA Sequence: MATWDEKAVTRRAKVAPAERMSKFLRHFTVVGDDYHAWNINYKKWENEEEEEEEEQPPPTPVSGEEGRAAAPDVAPAPGPAPRAPLDFRGMLRKLFSSHRFQVIIICLVVLDALLVLAELILDLKIIQPDKNNYAAMV
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 80%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  (May be suitable for use in other assays to be determined by the end user.)
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200µg/mL
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: HVCN1
• Official Symbol: HVCN1
• Synonyms: Hv1, VSOP, Voltage Sensor Domain-Only Protein, Hydrogen voltage-gated channel 1
• Gene ID: 84329
• mRNA Refseq: NM_001040107.2
• Protein Refseq: NP_001035196.1
• UniProt ID: Q96D96