Active Recombinant Human HTRA4 protein, His-tagged

• Cat.No.: HTRA4-793H
• Product Overview: Recombinant human full length HTRA4 protein was expressed in insect cells with C-terminus his tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
• Form: 0.05% Brij, 0.05% Calcium chloride, 0.79% Tris HCl, 0.88% Sodium chloride, 0.34%, pH 7.5.
• Bio-activity: Proteolytic activity of this product was documented by digestion of ß- casein. 0.5 mg ß-casein/ml are completely digested by 10 µg/ml HTRA4 within 18 hours at 37 centigrade.
• Molecular Mass: 52 kDa
• AA Sequence: MIRPQLRTAGLGRCLLPGLLLLLVPVLWAGAEKLHTQPSCPAVCQPTRCPALPTCALGTTPVFDLCRCCRVCPAAEREVCGGAQGQPCAPGLQCLQPLRPGFPSTCGCPTLGGAVCGSDRRTYPSMCALRAENRAARRLGKVPAVPVQWGNCGDTGTRSAGPLRRNYNFIAAVVEKVAPSVVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVVLQNGARYEAVVKDIDLKLDLAVIKIESNAELPVLMLGRSSDLRAGEFVVALGSPFSLQNTATAGIVSTKQRGGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVIGVNSLRVTDGISFAIPSDRVRQFLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKMHYPDFPDVSSGVYVCKVVEGTAAQSSGLRDHDVIVNINGKPITTTTDVVKALDSDSLSMAVLRGKDNLLLTVIPETINHHHHHH
• Purity: > 70% SDS-PAGE
• Storage: Store at -80 centigrade. Avoid freeze-thaw cycles.
• Concentration: 0.1 mg/mL
• Full Length: Full L.

Gene Information

• Gene Name: HtrA serine peptidase 4 [ Homo sapiens ]
• Official Symbol: HTRA4
• Synonyms: HTRA4; HtrA serine peptidase 4; probable serine protease HTRA4; FLJ90724
• Gene ID: 203100
• mRNA Refseq: NM_153692
• Protein Refseq: NP_710159
• MIM: 610700
• UniProt ID: P83105