Recombinant Human HTR2B Protein, GST-tagged

• Cat.No.: HTR2B-5243H
• Product Overview: Human HTR2B full-length ORF ( NP_000858.2, 1 a.a. - 481 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 80.7 kDa
• AA Sequence: MALSYRVSELQSTIPEHILQSTFVH VISSNWSGLQTESIPEEMKQIVEEQ GNKLHWAALLILMVIIPTIGGNTLV ILAVSLEKKLQYATNYFLMSLAVAD LLVGLFVMPIALLTIMFEAMWPLPL VLCPAWLFLDVLFSTASIMHLCAIS VDRYIAIKKPIQANQYNSRATAFIK ITVVWLISIGIAIPVPIKGIETDVD NPNNITCVLTKERFGDFMLFGSLAA FFTPLAIMIVTYFLTIHALQKKAYL VKNKPPQRLTWLTVSTVFQRDETPC SSPEKVAMLDGSRKDKALPNSGDET LMRRTSTIGKKSVQTISNEQRASKV LGIVFFLFLLMWCPFFITNITLVLC DSCNQTTLQMLLEIFVWIGYVSSGV NPLVYTLFNKTFRDAFGRYITCNYR ATKSVKTLRKRSSKIYFRNPMAENS KFFKKHGIRNGINPAMYQSPMRLRS STIQSSSIILLDTLLLTENEGDKTE ERVSYV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled [ Homo sapiens ]
• Official Symbol: HTR2B
• Synonyms: HTR2B; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled; 5 hydroxytryptamine (serotonin) receptor 2B; 5-hydroxytryptamine receptor 2B; 5 HT(2B); 5 HT2B; 5-HT-2B; 5-HT 2B receptor; serotonin receptor 2B; 5-hydroxytryptamine 2B receptor; 5-hydroxytryptamine receptor 2B variant b; 5-HT2B; 5-HT(2B)
• Gene ID: 3357
• mRNA Refseq: NM_000867
• Protein Refseq: NP_000858
• MIM: 601122
• UniProt ID: P41595