Recombinant Human HSPB3, His-tagged

• Cat.No.: HSPB3-3625H
• Product Overview: Recombinant human HSPB3 protein, fused to His-tag at N-terminus, was expressed in E.coli (1-150 aa).

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: HSPB3, also known as HSPL27, is a muscle-specific small heat shock protein. It is expressed preferentially in heart and skeletal muscle. Mammalian small heat shock proteins (sHSP) is a abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB3 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also Inhibitor of actin polymerization.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0), 5% glycerol, 1M Urea.
• Molecular Weight: 19.1 kDa (170aa)
• Purity: > 85 % by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay )
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAKIILRHLI EIPVRYQEEF EARGLEDCRL DHALYALPGP TIVDLRKTRA AQSPPVDSAA ETPPREGKSH FQILLDVVQF LPEDIIIQTF EGWLLIKAQH GTRMDEHGFI SRSFTRQYKL PDGVEIKDLS AVLCHDGILV VEVKDPVGTK
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: HSPB3 heat shock 27kDa protein 3 [ Homo sapiens ]
• Official Symbol: HSPB3
• Synonyms: HSPB3; HMN2C; DHMN2C; HSPL27; HspB3; heat shock 27kDa protein 3; heat shock protein beta-3; HSP 17; protein 3; OTTHUMP00000122478; heat shock 17 kDa protein
• Gene ID: 8988
• mRNA Refseq: NM_006308
• Protein Refseq: NP_006299
• MIM: 604624
• UniProt ID: Q12988
• Chromosome Location: 5q11.2