Recombinant Human HSD17B14, His-tagged

• Cat.No.: HSD17B14-13957H
• Product Overview: Recombinant Human HSD17B14 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: 17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-270a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 [ Homo sapiens ]
• Official Symbol: HSD17B14
• Synonyms: HSD17B14; hydroxysteroid (17-beta) dehydrogenase 14; dehydrogenase/reductase (SDR family) member 10 , DHRS10; 17-beta-hydroxysteroid dehydrogenase 14; retinal short chain dehydrogenase/reductase 3; retSDR3; SDR47C1; short chain dehydrogenase/reductase family 47C; member 1; 17-beta-HSD 14; 17-beta-hydroxysteroid dehydrogenase DHRS10; dehydrogenase/reductase SDR family member 10; retinal short-chain dehydrogenase/reductase 3; dehydrogenase/reductase (SDR family) member 10; retinal short-chain dehydrogenase/reductase retSDR3; short chain dehydrogenase/reductase family 47C, member 1; DHRS10
• Gene ID: 51171
• mRNA Refseq: NM_016246
• Protein Refseq: NP_057330
• MIM: 612832
• UniProt ID: Q9BPX1
• Chromosome Location: 19q13.33
• Function: estradiol 17-beta-dehydrogenase activity; nucleotide binding; oxidoreductase activity; protein binding; testosterone 17-beta-dehydrogenase (NADP+) activity