Recombinant Human HPGDS Protein, His-tagged

• Cat.No.: HPGDS-165H
• Product Overview: Active Recombinant Human HPGDS Protein with a N-terminal His tag was purified from an E. coli overexpression system.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.
• Molecular Mass: 24.3 kDa
• Purity: ≥95% estimated by SDS-PAGE
• Unit Definition: One unit of enzyme produces 1μmole of PGD2 per minute at 25 centigrade in 100 mM Tris-HCl, pH 8.0, 1 mM GSH, 1 mM magnesium chloride and 40 μM PGH.
• Storage Buffer: 50 mM sodium phosphate, pH 7.2, containing 20% glycerol, 100 mM sodium chloride, 1 mM DTT, and 0.5 mM EDTA

Gene Information

• Gene Name: HPGDS hematopoietic prostaglandin D synthase [ Homo sapiens (human) ]
• Official Symbol: HPGDS
• Synonyms: HPGDS; hematopoietic prostaglandin D synthase; GSTS; PGD2; PGDS; GSTS1; GSTS1-1; hematopoietic prostaglandin D synthase; GST class-sigma; epididymis secretory sperm binding protein; glutathione S-transferase sigma; glutathione-dependent PGD synthase; glutathione-dependent PGD synthetase; glutathione-requiring prostaglandin D synthase; hematopoietic prostaglandin D2 synthase; prostaglandin-H2 D-isomerase; EC 2.5.1.18; EC 5.3.99.2
• Gene ID: 27306
• mRNA Refseq: NM_014485
• Protein Refseq: NP_055300
• MIM: 602598
• UniProt ID: O60760