Recombinant Human HPGDS, His-tagged

• Cat.No.: HPGDS-360H
• Product Overview: A DNA sequence encoding the human PGDS (O60760) (Met1-Leu199) was expressed with a polyhistide tag at the C-terminus.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized from sterile PBS, pH7.4.
• Molecular Mass: The recombinant human PGDS consists of 205 amino acids and predicts a molecular mass of 24.2 KDa. It migrates as an approximately 25-29 KDa band in SDS-PAGE under reducing conditions.
• Protein length: Met1-Leu199
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >90 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: HPGDS hematopoietic prostaglandin D synthase [ Homo sapiens ]
• Official Symbol: HPGDS
• Synonyms: HPGDS; hematopoietic prostaglandin D synthase; glutathione S transferase sigma; GSTS; H PGDS; PGDS; GST class-sigma; prostaglandin-H2 D-isomerase; glutathione S-transferase sigma; glutathione-dependent PGD synthase; glutathione-dependent PGD synthetase; hematopoietic prostaglandin D2 synthase; glutathione-requiring prostaglandin D synthase
• Gene ID: 27306
• mRNA Refseq: NM_014485
• Protein Refseq: NP_055300
• MIM: 602598
• UniProt ID: O60760
• Chromosome Location: 4q22.2
• Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; prostanoid biosynthesis, organism-specific biosystem
• Function: calcium ion binding; glutathione transferase activity; isomerase activity; magnesium ion binding; prostaglandin-D synthase activity; protein homodimerization activity; transferase activity