Recombinant Human HOXC6, GST-tagged

• Cat.No.: HOXC6-13907H
• Product Overview: Recombinant Human HOXC6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-120a.a.
• Description: This gene belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5 non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: HOXC6 homeobox C6 [ Homo sapiens ]
• Official Symbol: HOXC6
• Synonyms: HOXC6; homeobox C6; homeo box C6 , HOX3, HOX3C; homeobox protein Hox-C6; homeo box 3C; homeo box C6; homeo box C8 protein; homeobox protein CP25; homeobox protein HHO.C8; homeobox protein Hox-3C; CP25; HOX3; HOX3C; HHO.C8
• Gene ID: 3223
• mRNA Refseq: NM_004503
• Protein Refseq: NP_004494
• MIM: 142972
• UniProt ID: P09630
• Chromosome Location: 12q13.13
• Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription corepressor activity