Recombinant Human HOMER1, His-tagged

• Cat.No.: HOMER1-405H
• Product Overview: Recombinant Homer 1 protein was expressed in E.coli and purified by using conventional chromatography techniques, 44.5 kDa (391 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-354 aa
• Description: Homer 1(Homer protein homolog 1) belongs to Homer family of proteins that regulate signal transduction through, and the trafficking of, glutamate receptors, as well as maintain and regulate extracellular glutamate levels in corticolimbic brain regions. The Homer 1 is enriched at excitatory synapses and binds group 1 metabotropic glutamate receptors (mGluRs).
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMGE QPIFSTRAHV FQIDPNTKKN WVPTSKHAVT VSYFYDSTRN VYRIISLDGS KAIINSTITP NMTFTKTSQK FGQWADSRAN TVYGLGFSSE HHLSKFAEKF QEFKEAARLA KEKSQEKMEL TSTPSQESAG GDLQSPLTPE SINGTDDERT PDVTQNSEPR AEPTQNALPF SHSSAISKHW EAELATLKGN NAKLTAALLE STANVKQWKQ QLAAYQEEAE RLHKRVTELE CVSSQANAVH THKTELNQTI QELEETLKLK EEEIERLKQE IDNARELQEQ RDSLTQKLQE VEIRNKDLEG QLSDLEQRLE KSQNEQEAFR NNLKTLLEIL DGKIFELTEL RDNLAKLLEC S
• Purity: > 90% by SDS - PAGE
• Concentration: 1.0 mg/ml (determined by Bradford assay)
• Form: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl 20% glycerol, and 1 mM DTT
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: HOMER1 homer homolog 1 (Drosophila) [ Homo sapiens ]
• Synonyms: HOMER1; homer homolog 1 (Drosophila); HOMER; SYN47; Ves-1; HOMER1A; HOMER1B; HOMER-1B; HOMER1C; HOMER1; Homer protein homolog 1; homer 1; OTTHUMP00000165782; homer, neuronal immediate early gene, 1.
• Gene ID: 9456
• mRNA Refseq: NM_004272
• Protein Refseq: NP_004263
• MIM: 604798
• UniProt ID: Q86YM7
• Chromosome Location: 5q14.2
• Function: protein binding