Recombinant Human Homer Homolog 3 (Drosophila), His-tagged

• Cat.No.: HOMER3-67H
• Product Overview: Recombinant humanHOMER3 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-361 aa
• Description: HOMER3, also knownas homer protein homolog 3, is a member of the HOMER family of postsynapticdensity scaffolding proteins that share a similar domain structure consistingof an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1domain which mediates protein-protein interactions, and a carboxy-terminalcoiled-coil domain and two leucine zipper motifs that are involved inself-oligomerization
• Form: Liquid. 20mMTris-HCl buffer (pH8.0) containing 30% glycerol, 0.15M NaCl, 1mM DTT
• Molecular Weight: 42.5 kDa (386aa),confirmed by MALDI-TOF
• Purity: > 90% by SDS -PAGE
• Concentration: 1 mg/ml (determinedby Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMMSTAR EQPIFSTRAH VFQIDPATKR NWIPAGKHAL TVSYFYDATR NVYRIISIGGAKAIINSTVT PNMTFTKTSQ KFGQWADSRA NTVYGLGFAS EQHLTQFAEK FQEVKEAARL AREKSQDGGELTSPALGLAS HQVPPSPLVS ANGPGEEKLF RSQSADAPGP TERERLKKML SEGSVGEVQW EAEFFALQDSNNKLAGALRE ANAAAAQWRQ QLEAQRAEAE RLRQRVAELE AQAASEVTPT GEKEGLGQGQ SLEQLEALVQTKDQEIQTLK SQTGGPREAL EAAEREETQQ KVQDLETRNA ELEHQLRAME RSLEEARAER ERARAEVGRAAQLLDVSLFE LSELREGLAR LAEAAP
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles

Gene Information

• Gene Name: HOMER3homer homolog 3 (Drosophila) [ Homo sapiens ]
• Official Symbol: HOMER3
• Synonyms: HOMER3; homer homolog 3 (Drosophila);homer protein homolog 3; HOMER 3; HOME3_HUMAN; HOMER 3; Homer 3D protein;Homer homolog 3 (Drosophila); Homer neuronal immediate early gene 3; Homerprotein homolog 3; Homer-3; Homer3; VESL3; Homer, neuronal immediate earlygene, 3; VESL3; HOMER-3
• Gene ID: 9454
• mRNA Refseq: NM_001145724
• Protein Refseq: NP_001139196
• MIM: 604800
• Uniprot ID: Q9NSC5
• Chromosome Location: 19p13.1
• Pathway: Glutamatergic synapse,organism-specific biosystem; Glutamatergic synapse, conserved biosystem; TCell Receptor Signaling Pathway, organism-specific biosystem
• Function: protein C-terminus binding; proteinbinding; protein domain specific binding