Recombinant Human Homeodomain Interacting Protein Kinase 4, GST-tagged

• Cat.No.: HIPK4-1024H
• Product Overview: Recombinant full-length human HIPK4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: HIPK4 or homeodomain interacting protein kinase 4 is a serine/threonine protein kinase that can act as a co-repressor of transcription factors. HIPK4 has been shown to phosphorylate the human p53 protein at serine 9, both in vitro and in vivo which is important for p53 mediated transcriptional repression. RT-PCR analysis showed moderate expression of HIPK4 in lung and white adipose tissue and weak expression in brain and liver.
• Applications: Kinase Assay; Western Blot
• Molecular Weight: 110 kDa
• Expression System: Sf9 insect cells using baculovirus
• Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Purity: >70%
• Concentration: 0.1 ug/ul
• Specific Activity: 202 RLU/min/ng
• Sequences: Full length
• Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: HIPK4 homeodomain interacting protein kinase 4 [ Homo sapiens ]
• Official Symbol: HIPK4
• Synonyms: HIPK4; homeodomain interacting protein kinase 4; FLJ32818; homeodomain-interacting protein kinase 4
• Gene ID: 147746
• mRNA Refseq: NM_144685
• Protein Refseq: NP_653286
• MIM: 611712
• UniProt ID: Q8NE63
• Chromosome Location: 19q13
• Function: ATP binding; protein serine/threonine kinase activity; nucleotide binding