Recombinant Human HNRPDL, GST-tagged

• Cat.No.: HNRPDL-13878H
• Product Overview: Recombinant Human HNRPDL protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-280a.a.
• Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: HNRPDL heterogeneous nuclear ribonucleoprotein D-like [ Homo sapiens ]
• Official Symbol: HNRPDL
• Synonyms: heterogeneous nuclear ribonucleoprotein D-like; 5037; Ensembl:ENSG00000152795; heterogeneous nuclear ribonucleoprotein D-like;hnRNP DL;hnRNP D-like;protein laAUF1;JKT41-binding protein;AU-rich element RNA-binding factor;A+U-rich element RNA binding factor; HNRNP; JKTBP; JKTBP2; laAUF1
• Gene ID: 9987
• mRNA Refseq: NM_001207000.1
• Protein Refseq: NP_001193929.1
• MIM: 607137
• UniProt ID: O14979
• Chromosome Location: 4q21.22
• Function: double-stranded DNA binding; nucleotide binding; poly(A) RNA binding; single-stranded DNA binding