Recombinant Human HNRNPH1 Protein

• Cat.No.: HNRNPH1-21H
• Product Overview: Recombinant Human HNRNPH1 Protein was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I.
• Form: Liquid. In 50 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl.
• Molecular Mass: ~32 kDa
• AA Sequence: NSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLHHHHHH
• Purity: >90%
• Storage: Short Term Storage at 4 centigrade, Long Term, please prepare aliquots with 20% glycerol and store at -20 to -80 centigrade. Avoid freeze/thaw cycles.
• Concentration: 0.2 mg/ml
• Official Full Name: Heterogeneous nuclear ribonucleoprotein H1
• Publications:
  HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction (2019)

Gene Information

• Gene Name: HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 [ Homo sapiens (human) ]
• Official Symbol: HNRNPH1
• Synonyms: HNRPH; HNRPH1; hnRNPH
• Gene ID: 3187
• mRNA Refseq: NM_001257293
• Protein Refseq: NP_001244222
• MIM: 601035
• UniProt ID: P31943