Recombinant Human HNRNPD Protein, Myc/DDK-tagged

• Cat.No.: HNRNPD-001H
• Product Overview: Recombinant protein of human heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) (HNRNPD), transcript variant 4 with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
• Molecular Mass: 30.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: HNRNPD heterogeneous nuclear ribonucleoprotein D [ Homo sapiens (human) ]
• Official Symbol: HNRNPD
• Synonyms: HNRNPD; heterogeneous nuclear ribonucleoprotein D; P37; AUF1; AUF1A; HNRPD; hnRNPD0; heterogeneous nuclear ribonucleoprotein D0; ARE-binding protein AUFI, type A; AU-rich element RNA binding protein 1, 37kDa; hnRNP D0
• Gene ID: 3184
• mRNA Refseq: NM_001003810
• Protein Refseq: NP_001003810
• MIM: 601324
• UniProt ID: Q14103