Recombinant Human HNRNPC, His-tagged

• Cat.No.: HNRNPC-3481H
• Product Overview: Recombinant human HNRNPC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Cat. No.: HNRNPC-3481H
• Description: HNRNPC, also known as hnRNP C1/C2, belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 30% glycerol
• Molecular Weight: 34.5 kDa (313aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
• Purity: > 85% by SDS - PAGE
• Concentration: 0.25 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MASNVTNKTD PRSMNSRVFI GNLNTLVVKK SDVEAIFSKY GKIVGCSVHK GFAFVQYVNE RNARAAVAGE DGRMIAGQVL DINLAAEPKV NRGKAGVKRS AAEMYGSSFD LDYDFQRDYY DRMYSYPARV PPPPPIARAV VPSKRQRVSG NTSRRGKSGF NSKSGQRGSS KSGKLKGDDL QAIKKELTQI KQKVDSLLEN LEKIEKEQSK QAVEMKNDKS EEEQSSSSVK KDETNVKMES EGGADDSAEE GDLLDDDDNE DRGDDQLELI KDDEKEAEEG EDDRDSANGE DDS
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) [ Homo sapiens ]
• Synonyms: heterogeneous nuclear ribonucleoprotein C (C1/C2); C1; C2; HNRNP; HNRPC; SNRPC; MGC104306; MGC105117; MGC117353; MGC131677; HNRNPC; hnRNP C1/C2; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; hnRNPC
• Gene ID: 3183
• mRNA Refseq: NM_001077442
• Protein Refseq: NP_001070910
• MIM: 164020
• UniProt ID: 07910
• Chromosome Location: 14q11.2
• Pathway: Spliceosome; Gene Expression; mRNA Processing
• Function: RNA binding; identical protein binding; nucleotide binding; protein binding