Recombinant Human HNMT
Cat.No. : | HNMT-27547TH |
Product Overview : | Recombinant full length Human HNMT, expressed in Saccharomyces cerevisiae; amino acids 1-292, 292 amino acids, MWt 33.3 kDa. Protein is tagged with 26 kDa proprietary tag. |
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Species : | Human |
Tag : | Non |
Protein Length : | 1-292 a.a. |
Description : | In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKL PGIIGRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQY PGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWH KETSSEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPAT LKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQ DDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCF IDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA |
Full Length : | Full L. |
Gene Name | HNMT histamine N-methyltransferase [ Homo sapiens ] |
Official Symbol | HNMT |
Synonyms | HNMT; histamine N-methyltransferase; |
Gene ID | 3176 |
mRNA Refseq | NM_001024074 |
Protein Refseq | NP_001019245 |
MIM | 605238 |
Uniprot ID | P50135 |
Chromosome Location | 2q22.1 |
Pathway | Histidine metabolism, organism-specific biosystem; Histidine metabolism, conserved biosystem; histamine degradation, conserved biosystem; |
Function | histamine N-methyltransferase activity; methyltransferase activity; transferase activity; |
◆ Recombinant Proteins | ||
HNMT-2116R | Recombinant Rhesus monkey HNMT Protein, His-tagged | +Inquiry |
HNMT-5216C | Recombinant Chicken HNMT | +Inquiry |
HNMT-2878R | Recombinant Rat HNMT Protein | +Inquiry |
Hnmt-4643M | Recombinant Mouse Hnmt protein, His&Myc-tagged | +Inquiry |
HNMT-22H | Active Recombinant Human HNMT protein, His-tagged | +Inquiry |
◆ Native Proteins | ||
HNMT-1355R | Active Native Rat HNMT Protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
HNMT-5455HCL | Recombinant Human HNMT 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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