Recombinant Human HMGN1, His-tagged

• Cat.No.: HMGN1-2050H
• Product Overview: Recombinant human HMGN1 protein fused to His-tag was expressed inE.coliand purified by using conventional chromatography techniques. 11.7 kDa (108aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. This Protein is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl, 1mM DTT, 0.1mM PMSF.
• Purity: > 95% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MPKRKVSSAE GAAKEEPKRR SARLSAKPPA KVEAKPKKAA AKDKSSDKKV QTKGKRGAKG KQAEVANQET KEDLPAENGE TKTEESPASDEAGEKEAKSD LEHHHHHH.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: HMGN1 high-mobility group nucleosome binding domain 1 [ Homo sapiens ]
• Synonyms: high-mobility group nucleosome binding domain 1; HMG14; FLJ27265; FLJ31471; MGC104230; MGC117425; HMGN1; non-histone chromosomal protein HMG-14; nonhistone chromosomal protein HMG-14; high-mobility group (nonhistone chromosomal) protein 14; high mobility group nucleosome-binding domain-containing protein 1; High-mobility group nucleosome-binding domain-containing protein 1
• Gene ID: 3150
• mRNA Refseq: NM_004965
• Protein Refseq: NP_004956
• MIM: 163920
• UniProt ID: P05114
• Chromosome Location: 21q22.3; 21q22.2
• Function: DNA binding; RNA polymerase II transcription factor activity; positive transcription elongation factor activity