Recombinant Human HMGCR protein, GST-tagged

• Cat.No.: HMGCR-20H
• Product Overview: Recombinant Human HMGCR(426-888 (N-terminal truncation)) fused with GST tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 426-888 a.a.
• Form: Supplied as a solution containing 250 μg protein in 50 mM Tris pH 7.5, with 5 mM DTT, 1:200 Protease Inhibitor Cocktail and 50% (w/v) glycerol.
• Molecular Mass: 76.5 kDa
• Purity: Purity ≥90% estimated by SDS-PAGE
• Unit Definition: One unit will convert 1.0 μmole of NADPH to NADP+ per minute at 37 centigrade.
• Stability: 9 months
• Storage: Store at -80 centigrade

Gene Information

• Gene Name: HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [ Homo sapiens ]
• Official Symbol: HMGCR
• Synonyms: HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; 3 hydroxy 3 methylglutaryl Coenzyme A reductase; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase; 3 hydroxy 3 methylglutaryl CoA reductase (NADPH); hydroxymethylglutaryl CoA reductase; HMG-CoA reductase; hydroxymethylglutaryl-CoA reductase; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH); LDLCQ3
• Gene ID: 3156
• mRNA Refseq: NM_000859
• Protein Refseq: NP_000850
• UniProt ID: P04035
• Chromosome Location: 5q13.3-q14
• Pathway: Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, organism-specific biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, conserved biosystem; Cholesterol Biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem
• Function: NADP binding; hydroxymethylglutaryl-CoA reductase (NADPH) activity; oxidoreductase activity