Recombinant Human HMG20A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HMG20A-6565H
• Product Overview: HMG20A MS Standard C13 and N15-labeled recombinant protein (NP_060670) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 40.1 kDa
• AA Sequence: MENLMTSSTLPPLFADEDGSKESNDLATTGLNHPEVPYSSGATSSTNNPEFVEDLSQGQLLQSESSNAAEGNEQRHEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQDAARQATHDHEKETEVKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQVLTSSFASMPLPGSGETPTVDTIDSYMNRLHSIILANPQDNENFIATVREVVNRLDRTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HMG20A high mobility group 20A [ Homo sapiens (human) ]
• Official Symbol: HMG20A
• Synonyms: HMG20A; high mobility group 20A; high mobility group protein 20A; FLJ10739; HMG box domain containing 1; HMGX1; HMGXB1; high-mobility group 20A; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1
• Gene ID: 10363
• mRNA Refseq: NM_018200
• Protein Refseq: NP_060670
• MIM: 605534
• UniProt ID: Q9NP66