Recombinant Human HLA-DRB1 protein, His-tagged

• Cat.No.: HLA-DRB1-01H
• Product Overview: Recombinant protein of human HLA-DRB1 was expressed in Baculovirus, with a His-Tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 30-227aa
• Description: HLA-DRB1, also known as major histocompatibility complex, class II, DR beta 1 precursor, belongs to the human leukocyte antigen (HLA) class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins to T helper cells. It helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria. It is associated with an increased incidence of rheumatoid arthritis. Recombinant human HLA-DRB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
• Form: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol.
• Molecular Mass: 24 kDa (207aa)
• AA Sequence: ADPGDTRPRF LWQPKRECHF FNGTERVRFL DRYFYNQEES VRFDSDVGEF RAVTELGRPD AEYWNSQKDI LEQARAAVDT YCRHNYGVVE SFTVQRRVQP KVTVYPSKTQ PLQHHNLLVC SVSGFYPGSI EVRWFLNGQE EKAGMVSTGL IQNGDWTFQT LVMLETVPRS GEVYTCQVEH PSVTSPLTVE WRARSESAQS KHHHHHH
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
• Purity: > 85% by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml

Gene Information

• Gene Name: HLA-DRB1 major histocompatibility complex, class II, DR beta 1 [ Homo sapiens (human) ]
• Official Symbol: HLA-DRB1
• Synonyms: Major histocompatibility complex, class II, DR beta 1, HLA-DRB1, DRB1, HLA-DR1B, HLA-DRB, SS1
• Gene ID: 3123
• mRNA Refseq: NM_002124
• Protein Refseq: NP_002115
• MIM: 142857
• UniProt ID: P01911