Recombinant Human HIST1H4F, His-tagged

Cat.No. : HIST1H4F-13799H
Product Overview : Recombinant Human HIST1H4F protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Availability April 03, 2025
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Species : Human
Source : E.coli
Tag : His
Protein Length : 1-103a.a.
Description : Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name HIST1H4F histone cluster 1, H4f [ Homo sapiens ]
Official Symbol HIST1H4F
Synonyms histone cluster 1, H4f; 4783; Ensembl:ENSG00000198327; histone H4;histone 1, H4f;H4 histone family, member C; H4; H4/c; H4FC
Gene ID 8361
mRNA Refseq NM_003540.3
Protein Refseq NP_003531.1
MIM 602824
UniProt ID B2R4R0
Chromosome Location 6p22.1
Pathway Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Amyloids, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; Disease, organism-specific biosystem;

Not For Human Consumption!

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